BT LAB

Artikelnummer: BT-E2894Hu-96T

Human Chromobox Protein Homolog 2, CBX2 ELISA Kit, 96T

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed: 21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed: 21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, acting as activator of NR5A1 expression (PubMed: 19361780).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:3.71ng/L

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Application:ELISA

Detection Target:CBX2

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Detection Range: 7-1500ng/L

Research Areas:Epigenetics and Nuclear Signaling

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Test Principle:Sandwich

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Assay Time:1h 30m

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