BT LAB

Artikelnummer: BT-E5453Hu-96T

Human Immediate Early Response Gene 5 Protein, IER5 ELISA Kit, 96T

Plays a role as a transcription factor (PubMed: 22132193, PubMed: 25355627). Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner (PubMed: 25355627, PubMed: 25816751). Mediates negative transcriptional regulation of CDC25B expression (PubMed: 22132193). Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A (PubMed: 25816751, PubMed: 26496226). Involved in the regulation of cell proliferation and resistance to thermal stress (PubMed: 22132193, PubMed: 25355627, PubMed: 26496226). Involved in the cell cycle checkpoint and survival in response to ionizing radiation (PubMed: 19238419, PubMed: 22132193). Associates with chromatin to the CDC25B promoter (PubMed: 22132193).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:5.32ng/L

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Application:ELISA

Detection Target:IER5

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Detection Range: 10-2000ng/L

Research Areas:Signal Transduction

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Assay Time:1h 30m

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