{"product_id":"3hao-polyclonal-antibody-20ul","title":"3HAO Polyclonal Antibody, 20ul","description":"\u003cp\u003e3-Hydroxyanthranilate 3|4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508855484789,"sku":"BT-AP08399-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/3hao-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}