{"product_id":"actinin-alpha1-polyclonal-antibody-100ulbt-ap00214","title":"Actinin-Alpha1 Polyclonal Antibody, 100ul[BT-AP00214]","description":"\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516115038581,"sku":"BT-AP00214-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/actinin-alpha1-polyclonal-antibody-100ulbt-ap00214","provider":"LabCart Life Science","version":"1.0","type":"link"}