{"product_id":"actinin-alpha2-3-polyclonal-antibody-100ul","title":"Actinin-Alpha2\/3 Polyclonal Antibody, 100ul","description":"\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for ACTN2.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516115136885,"sku":"BT-AP00217-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/actinin-alpha2-3-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}