BT LAB

Artikelnummer: BT-AP14120-20ul

ACY1 Polyclonal Antibody, 20ul

This gene encodes a cytosolic| homodimeric| zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group| and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1| a region reduced to homozygosity in small-cell lung cancer (SCLC)| and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart| and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, ELISA

Detection Target:ACY1

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Research Areas:Metabolism; Signal transduction

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Reactivity:Human, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

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