BT LAB

Artikelnummer: BT-MCA0140-50ul

AIF-M1 Monoclonal Antibody, 50ul

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, IHC-p, IF, ICC, FCM, ELISA

Detection Target:AIFM1

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Research Areas:Cell Biology; Epigenetics and Nuclear Signaling; Cancer; Metabolism

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Reactivity:Human,Mouse,Rat,Monkey

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Clonality:Monoclonal

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Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

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