{"product_id":"als2-polyclonal-antibody-50ul","title":"ALS2 Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe protein encoded by this gene contains an ATS1\/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515687645557,"sku":"BT-AP06209-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/als2-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}