{"product_id":"atrphospho-thr1989-rabbit-polyclonal-antibody-20ul","title":"ATR(Phospho-Thr1989) Rabbit Polyclonal Antibody, 20ul","description":"\u003cp\u003eThe protein encoded by this gene belongs the PI3\/PI4-kinase family| and is most closely related to ATM| a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1| checkpoint proteins RAD17| and RAD9| as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516981883253,"sku":"BT-AP06215-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/de\/products\/atrphospho-thr1989-rabbit-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}