{"product_id":"bag-3-polyclonal-antibody-100ulbt-ap00819","title":"Bag-3 Polyclonal Antibody, 100ul[BT-AP00819]","description":"\u003cp\u003eBAG proteins compete with Hip for binding to the Hsc70\/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516135059829,"sku":"BT-AP00819-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/bag-3-polyclonal-antibody-100ulbt-ap00819","provider":"LabCart Life Science","version":"1.0","type":"link"}