{"product_id":"cas-polyclonal-antibody-100ul","title":"CAS Polyclonal Antibody, 100ul","description":"\u003cp\u003eProteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha\/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein (chromosome segregation 1 like) may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for CSE1L.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516144103797,"sku":"BT-AP01176-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/cas-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}