{"product_id":"caspase-8-polyclonal-antibody-100ul","title":"Caspase-8 Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain| a large protease subunit| and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls| which implicated the role in neurodegenerative diseases. Many alt\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508650979701,"sku":"BT-AP00885-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/caspase-8-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}