Artikelnummer: E-AB-66490_60μL-ES

CAV1 Polyclonal Antibody, 60 μL

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

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Produktspezifikation

Grundlegende Informationen

Marken: Elabscience

Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Herkunftsort: China

Technical Specifications

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Concentration:1mg/mL

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Calculated Molecular Weight:17kDa/20kDa

Observed Molecular Weight:20kDa/23kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:17kDa/20kDa

Dilution:WB 1:500-1:2000

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Konzentration: 1mg/mL

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