{"product_id":"caveolin-1-polyclonal-antibody-100ulbt-ap01254","title":"Caveolin-1 Polyclonal Antibody, 100ul[BT-AP01254]","description":"\u003cp\u003eThe scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42\/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516146200949,"sku":"BT-AP01254-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/caveolin-1-polyclonal-antibody-100ulbt-ap01254","provider":"LabCart Life Science","version":"1.0","type":"link"}