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Artikelnummer: E-AB-90054_60μL-ES
CHRNA2 Polyclonal Antibody, 60 μL
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
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Concentration:1mg/mL
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Calculated Molecular Weight:58kDa/59kDa
Observed Molecular Weight:60kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:58kDa/59kDa
Dilution:WB 1:500-1:2000
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Konzentration: 1mg/mL
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