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Artikelnummer: E-AB-91633_200μL-ES
CSK Polyclonal Antibody, 200 μL
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR and B-cell receptor (BCR by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
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Concentration:1mg/mL
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Calculated Molecular Weight:50kDa
Observed Molecular Weight:50kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:50kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200
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Konzentration: 1mg/mL
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Anwendung: WB;IHC;IF
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