{"product_id":"dd3-polyclonal-antibody-20ul","title":"DD3 Polyclonal Antibody, 20ul","description":"\u003cp\u003eAKR1C3 (aldo-keto reductase family 1 member C3) encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and\/or differentiation. AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for AKR1C3.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508036448629,"sku":"BT-AP02531-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/dd3-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}