{"product_id":"dok-6-polyclonal-antibody-50ul","title":"Dok-6 Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe downstream of kinase family (Dok-1-7) are members of a class of \"docking\" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56513655013749,"sku":"BT-AP02702-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/dok-6-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}