{"product_id":"e2f-1-acetyl-k125-polyclonal-antibody-100ul","title":"E2F-1 (Acetyl-K125) Polyclonal Antibody, 100ul","description":"\u003cp\u003eThe protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.  This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518267011445,"sku":"BT-AP15353-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_2.jpg?v=1766710711","url":"https:\/\/www.labcart.com\/de\/products\/e2f-1-acetyl-k125-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}