{"product_id":"fgd4-rabbit-polyclonal-antibody-100ul","title":"FGD4 Rabbit Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain| which together with its Dbl homology domain and one of its pleckstrin homology domains| can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain| and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum| an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H)| a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56517130092917,"sku":"BT-AP10033-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/fgd4-rabbit-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}