BT LAB

Artikelnummer: BT-E2284Hu-96T

Human Adenomatosis Polyposis Coli Protein, APC ELISA Kit, 96T

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:1.16ng/ml

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Storage:2-8ºC

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Features and Capabilities

Application:ELISA

Detection Target:APC

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Detection Range: 2-700ng/ml

Research Areas:Others

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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