BT LAB

Artikelnummer: BT-E6544Hu-96T

Human Beta-Adrenergic Receptor Kinase 1, ADRBK1 ELISA Kit, 96T

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PubMed: 19715378). Key regulator of LPAR1 signaling (PubMed: 19306925). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PubMed: 19306925). Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed: 19306925). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity). Inhibits relaxation of airway smooth muscle in response to blue light (PubMed: 30284927).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:4.95ng/L

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Application:ELISA

Detection Target:GRK2

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Detection Range: 10-2000ng/L

Research Areas:Signal Transduction

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Test Principle:Sandwich

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Assay Time:1h 30m

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