BT LAB

Artikelnummer: BT-E6610Hu-96T

Human Cartilage Intermediate Layer Protein 1, CILP ELISA Kit, 96T

Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:26.34ng/L

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Application:ELISA

Detection Target:CILP

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Detection Range: 50-10000ng/L

Research Areas:Signal Transduction

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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