BT LAB

Artikelnummer: BT-E2899Hu-96T

Human Claspin, CLSPN ELISA Kit, 96T

Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex (pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.026ng/ml

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Application:ELISA

Detection Target:CLSPN

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Detection Range: 0.05-20ng/ml

Research Areas:Epigenetics and Nuclear Signaling

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Test Principle:Sandwich

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Assay Time:1h 30m

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