{"product_id":"human-coronin-1c-coro1c-elisa-kit-96t","title":"Human Coronin 1C, CORO1C ELISA Kit, 96T","description":"\u003cp\u003ePlays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed: 25074804, PubMed: 25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed: 25074804, PubMed: 25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (By similarity). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed: 30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed: 30220460). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (By similarity). Required for normal distribution of mitochondria within cells (By similarity). [Isoform 3]: Involved in myogenic differentiation.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592504422773,"sku":"BT-E2450Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-coronin-1c-coro1c-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}