BT LAB

Artikelnummer: BT-E5159Hu-96T

Human Cytochrome P450 26A1, CYP26A1 ELISA Kit, 96T

A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed: 22020119, PubMed: 9228017, PubMed: 9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed: 26937021).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:4.9ng/L

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Application:ELISA

Detection Target:CYP26A1

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Detection Range: 10-2000ng/L

Research Areas:Others

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Assay Time:1h 30m

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