{"product_id":"human-dna-binding-protein-ikaros-ikzf1-elisa-kit-96t","title":"Human DNA-binding Protein Ikaros, IKZF1 ELISA Kit, 96T","description":"\u003cp\u003eTranscription regulator of hematopoietic cell differentiation (PubMed: 17934067). Binds gamma-satellite DNA (PubMed: 17135265, PubMed: 19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI\/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed: 17135265, PubMed: 17934067).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592656433525,"sku":"BT-E5197Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-dna-binding-protein-ikaros-ikzf1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}