BT LAB

Artikelnummer: BT-E5237Hu-96T

Human Endoplasmic Reticulum Aminopeptidase 1, ERAP1 ELISA Kit, 96T

Aminopeptidase that plays a central role in Peptide trimming, a step required for the generation of most HLA class I-binding Peptides. Peptide trimming is essential to customize longer precursor Peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and Peptides with a hydrophobic C-terminus, while it has weak activity toward Peptides with charged C-terminus. May play a role in the inactivation of Peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Application:ELISA

Detection Target:ERAP1

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Detection Range: 0.05-20ng/ml

Research Areas:Immunology

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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