{"product_id":"human-estrogen-receptor-beta-er-beta-elisa-kit-96t","title":"Human Estrogen Receptor Beta, ER-beta ELISA Kit, 96T","description":"\u003cp\u003eNuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed: 20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592527196533,"sku":"BT-E3287Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-estrogen-receptor-beta-er-beta-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}