{"product_id":"human-eyes-absent-homolog-2-eya2-elisa-kit-96t","title":"Human Eyes Absent Homolog 2, EYA2 ELISA Kit, 96T","description":"\u003cp\u003eFunctions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (PubMed: 12500905, PubMed: 23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed: 19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1 (PubMed: 12500905).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592658104693,"sku":"BT-E5272Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-eyes-absent-homolog-2-eya2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}