{"product_id":"human-hypoxia-inducible-factor-3-alpha-hif-3a-elisa-kit-96t","title":"Human Hypoxia-inducible Factor 3 Alpha, HIF-3A ELISA Kit, 96T","description":"\u003cp\u003eActs as a transcriptional regulator in adaptive response to low oxygen tension. Acts as a regulator of hypoxia-inducible gene expression (PubMed: 11573933, PubMed: 16126907, PubMed: 19694616, PubMed: 20416395, PubMed: 21069422). Functions as an inhibitor of angiogenesis in hypoxic cells of the cornea. Plays a role in the development of the cardiorespiratory system. May also be involved in apoptosis (By similarity). [Isoform 2]: Attenuates the ability of transcription factor HIF1A to bind to hypoxia-responsive elements (HRE) located within the enhancer\/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation. Also inhibits hypoxia-inducible ARNT-mediated gene expression. [Isoform 3]: Attenuates the ability of transcription factor HIF1A to bind to hypoxia-responsive elements (HRE) located within the enhancer\/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation. [Isoform 4]: Attenuates the ability of transcription factor HIF1A and EPAS1\/HIF2A to bind to hypoxia-responsive elements (HRE) located within the enhancer\/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation (PubMed: 16126907, PubMed: 17998805, PubMed: 19694616, PubMed: 20416395). May act as a tumor suppressor and inhibits malignant cell transformation (PubMed: 17998805). [Isoform 5]: Attenuates the ability of transcription factor HIF1A to bind to hypoxia-responsive elements (HRE) located within the enhancer\/promoter of hypoxia-inducible target genes and hence inhibits HRE-driven transcriptional activation.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592628089205,"sku":"BT-E4763Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-hypoxia-inducible-factor-3-alpha-hif-3a-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}