{"product_id":"human-indoleamine-2-3-dioxygenase-ido-elisa-kit-96t","title":"Human Indoleamine 2, 3-dioxygenase, IDO ELISA Kit , 96T","description":"\u003cp\u003eCatalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed: 17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed: 25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed: 25691885). Acts as a suppressor of anti-tumor immunity (PubMed: 23103127, PubMed: 25157255, PubMed: 14502282, PubMed: 25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PubMed: 25691885). Protects the fetus from maternal immune rejection (PubMed: 25691885).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592477520245,"sku":"BT-E0796Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-indoleamine-2-3-dioxygenase-ido-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}