BT LAB

Artikelnummer: BT-E2781Hu-96T

Human Klotho, KL ELISA Kit, 96T

May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). The Klotho Peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:2.47pg/ml

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Storage:2-8ºC

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Features and Capabilities

Application:ELISA

Detection Target:KL

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Detection Range: 5-1000pg/ml

Research Areas:Developmental Biology

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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