{"product_id":"human-liver-carboxylesterase-1-ces1-elisa-kit-96t","title":"Human Liver Carboxylesterase 1, CES1 ELISA Kit, 96T","description":"\u003cp\u003eInvolved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine (PubMed: 7980644). Catalyzes the transesterification of cocaine to form cocaethylene (PubMed: 7980644). Displays fatty acid ethyl ester Synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate (PubMed: 7980644). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed: 21049984). Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process (PubMed: 18762277, PubMed: 16024911, PubMed: 11015575, PubMed: 16971496). First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile (PubMed: 18762277, PubMed: 18599737, PubMed: 16971496).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592500064629,"sku":"BT-E2395Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-liver-carboxylesterase-1-ces1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}