{"product_id":"human-mothers-against-decapentaplegic-homolog-2-smad2-elisa-kit-96t","title":"Human Mothers Against Decapentaplegic Homolog 2, SMAD2 ELISA Kit, 96T","description":"\u003cp\u003eReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2\/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592514154869,"sku":"BT-E2911Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-mothers-against-decapentaplegic-homolog-2-smad2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}