BT LAB

Artikelnummer: BT-E0639Hu-96T

Human Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit , 96T

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Features and Capabilities

Application:ELISA

Detection Target:SMAD7

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Detection Range: 0.05-20ng/ml

Research Areas:Signal Transduction; Epigenetics and Nuclear Signaling

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Reactivity:Human

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Test Principle:Sandwich

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Assay Time:1h 30m

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