{"product_id":"human-mothers-against-decapentaplegic-homolog-7-smad7-elisa-kit-96t","title":"Human Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit , 96T","description":"\u003cp\u003eAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592473227637,"sku":"BT-E0639Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-mothers-against-decapentaplegic-homolog-7-smad7-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}