{"product_id":"human-pancreas-duodenum-homeobox-protein-1-pdx1-elisa-kit-96t","title":"Human Pancreas Duodenum Homeobox Protein 1, PDX1 ELISA Kit, 96T","description":"\u003cp\u003eActivates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592756343157,"sku":"BT-E6802Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-pancreas-duodenum-homeobox-protein-1-pdx1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}