{"product_id":"human-protein-phosphatase-mg2-mn2-dependent-1d-ppm1d-elisa-kit-96t","title":"Human Protein Phosphatase, Mg2+, Mn2+ Dependent 1D, PPM1D ELISA Kit, 96T","description":"\u003cp\u003eInvolved in the negative regulation of p53 expression (PubMed: 23242139). Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed: 15870257, PubMed: 16311512). Mediates MAPK14 dephosphorylation and inactivation (PubMed: 21283629). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592763781493,"sku":"BT-E7328Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-protein-phosphatase-mg2-mn2-dependent-1d-ppm1d-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}