{"product_id":"human-protein-s100-a4-s100a4-elisa-kit-96t","title":"Human Protein S100-A4, S100A4 ELISA Kit , 96T","description":"\u003cp\u003eCalcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy (PubMed: 16707441, PubMed: 23752197, PubMed: 30713770). Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA\/MYH9 (PubMed: 16707441). Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis (By similarity). Modulates also the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels (PubMed: 23752197). Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes (By similarity). In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors (PubMed: 30713770, PubMed: 26654597).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592678781301,"sku":"BT-E6000Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-protein-s100-a4-s100a4-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}