{"product_id":"human-sialidase-4-neu4-elisa-kit-96t","title":"Human Sialidase-4, NEU4 ELISA Kit, 96T","description":"\u003cp\u003eExo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides. Efficiently hydrolyzes gangliosides including alpha-(2-\u0026gt;3)-sialylated GD1a and GM3 and alpha-(2-\u0026gt;8)-sialylated GD3 (PubMed: 15847605, PubMed: 21521691, PubMed: 15213228). Hydrolyzes poly-alpha-(2-\u0026gt;8)-sialylated neural cell adhesion molecule NCAM1 likely at growth cones, suppressing neurite outgrowth in hippocampal neurons (By similarity). May desialylate sialyl Lewis A and X antigens at the cell surface, down-regulating these glycan epitopes recognized by SELE\/E selectin in the initiation of cell adhesion and extravasation (PubMed: 21521691). Has sialidase activity toward mucin, fetuin and sialyllactose (PubMed: 15847605).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592522150261,"sku":"BT-E3141Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-sialidase-4-neu4-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}