{"product_id":"human-sterol-regulatory-element-binding-protein-2-srebf2-elisa-kit-96t","title":"Human Sterol Regulatory Element-binding Protein 2, SREBF2 ELISA Kit , 96T","description":"\u003cp\u003e[Sterol regulatory element-binding protein 2]: Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 2), which is embedded in the endoplasmic reticulum membrane (PubMed: 32322062). Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis (PubMed: 32322062). [Processed sterol regulatory element-binding protein 2]: Key transcription factor that regulates expression of genes involved in cholesterol biosynthesis (PubMed: 12177166, PubMed: 32322062). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3') (PubMed: 7903453, PubMed: 12177166). Regulates transcription of genes related to cholesterol synthesis pathway (PubMed: 12177166, PubMed: 32322062). \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592699228533,"sku":"BT-E6225Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/human-sterol-regulatory-element-binding-protein-2-srebf2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}