{"product_id":"jdp2phospho-thr148-polyclonal-antibody-50ul","title":"JDP2(Phospho Thr148) Polyclonal Antibody, 50ul","description":"\u003cp\u003eComponent of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3\/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.,Belongs to the bZIP family. ATF subfamily.,Contains 1 bZIP domain.,subunit:Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515811901813,"sku":"BT-AP10570-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/jdp2phospho-thr148-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}