{"product_id":"jip-1phospho-thr103-polyclonal-antibody-50ul","title":"JIP-1(Phospho Thr103) Polyclonal Antibody, 50ul","description":"\u003cp\u003eThis gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515811934581,"sku":"BT-AP10573-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/jip-1phospho-thr103-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}