{"product_id":"kir3-1phospho-ser185-polyclonal-antibody-20ul","title":"KIR3.1(Phospho Ser185) Polyclonal Antibody, 20ul","description":"\u003cp\u003ePotassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512964821365,"sku":"BT-AP10697-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/kir3-1phospho-ser185-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}