{"product_id":"lambda-5-polyclonal-antibody-50ulbt-ap04931","title":"Lambda 5 Polyclonal Antibody, 50ul[BT-AP04931]","description":"\u003cp\u003eLambda 5 (also called Immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. SL chain is also part of a quality control mechanism that tests a m-chain for its ability to pair with conventional L chains. It can form Ig-like complexes with the heavy (H) chain, the DHJHC m-protein or the p55 chain. Production of the surrogate light chain begins at the stage of pro-B cells, continues during the pre-B-cell stage and halts at the immature B cell stage. Once pre-BCR is expressed, SL chain expression is turned off. As pre-B II cells proliferate, SL is diluted out, thus limiting pre-BCR formation. Lambda 5 is critical for B cell development in mammals. Expression of Lambda 5 is highest in liver, pre- B-lymphocytes and bone marrow, the major source of B cell precursors.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514008154485,"sku":"BT-AP04931-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/lambda-5-polyclonal-antibody-50ulbt-ap04931","provider":"LabCart Life Science","version":"1.0","type":"link"}