{"product_id":"limk-1-2phospho-thr508-505-polyclonal-antibody-100ul","title":"LIMK-1\/2(Phospho Thr508\/505) Polyclonal Antibody, 100ul","description":"\u003cp\u003eThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine\/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518326485365,"sku":"BT-AP10911-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_2.jpg?v=1766710711","url":"https:\/\/www.labcart.com\/de\/products\/limk-1-2phospho-thr508-505-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}