{"product_id":"limk-1phospho-thr508-polyclonal-antibody-20ul","title":"LIMK-1(Phospho Thr508) Polyclonal Antibody, 20ul","description":"\u003cp\u003eThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine\/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512969736565,"sku":"BT-AP10908-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/limk-1phospho-thr508-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}