Elabscience

Artikelnummer: E-AB-70261_200μL-ES

Mineralocorticoid receptor Polyclonal Antibody, 200 μL

This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1.3 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:200-1:800

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Application:IHC

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Research Areas:Signal Transduction; Cardiovascular; Epigenetics and Nuclear Signaling

Species Reactivity:Human; Mouse; Rat

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Target Synonym:Aldosterone receptor;MCR;MGC133092;Mineralocorticoid receptor;MLR;MR;NR3 C2;NR3C2;NR3C2 protein;Nuclear receptor subfamily 3 group C member 2

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Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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