{"product_id":"mlklphospho-s358-polyclonal-antibody-20ul","title":"MLKL(Phospho S358) Polyclonal Antibody, 20ul","description":"\u003cp\u003eThis gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518385271157,"sku":"BT-AP11379-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_2.jpg?v=1766710711","url":"https:\/\/www.labcart.com\/de\/products\/mlklphospho-s358-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}